University of Texas Health Science Center San Antonio
San Antonio, Texas, United States
Biography - I graduated from the University of Illinois with a B.S in chemistry in 1983, finished his Ph.D. thesis work from the University of Chicago in 1990, and graduated from Loyola Medical School in 1992. I completed an internship year at the University of Chicago and a radiation oncology residency at Washington University School of Medicine, the Mallinckrodt Institute of Radiology. After residency I was an Assistant Professor at Washington University for four years and than accepted a position as the Chief of the Molecular Radiation Oncology Section at the National Cancer Institute in the Radiation Oncology Branch that lasted eight years. Currently I am a Professor of Radiation and the clinical chief of the Radiation Oncology Northwestern University Feinberg School of Medicine.
Research - The central theme of the laboratory is the potential relationship of intracellular pro-proliferative / pro-survival factors and how tumor cells respond to therapeutic modalities. We hypothesize that specific pro-survival pathways, both alone and more likely in combination, and their upstream signaling factors are potential molecular targets to improve the cytotoxic effects of anti-cancer agents including but not limited to ionizing radiation. These challenges have led our laboratory to concentrate its efforts into the role that longevity genes might play a role in carcinogenesis. The overarching theme of this aspect of the laboratory is based on one of the fundamental observations in Oncology. That is: cancer is a disease of aging, and the rate of malignancies increases significantly as a function of age
Disclosures:
Sunday, September 29, 2024
3:07 PM – 3:17 PM ET
Monday, September 30, 2024
3:00 PM – 4:00 PM ET