3536 - AI-Assisted 3D Printing Transvaginal Template Guidance for Interstitial Brachytherapy in Patients with Cervical Cancer with Parametrial Invasion

H. Li¹, X. Li¹, J. Zhang¹, Y. Dai², H. Lin³, X. Xie¹, and M. Yang¹; ¹Department of Gynecology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China, ²Department of Radiation Physics, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China, ³Department of Obstetrics and gynecology, Putian First Hospital, Putian, Fujian, China

Purpose/Objective(s): This is a retrospective study to show the safety and efficacy of using AI-assisted transvaginal 3D printed templates for guiding interstitial BT as a component of definitive RT in patients with cervical cancer with parametrial invasion. Materials/

Methods: The localization data of 17 patients from computed tomography scanning were collected and imported into the software. Automated configuration of individualized 3D printing templates using AI-assisted technology according to the specific anatomical morphology and volume of the target. The accuracy of the needle insertion paths and needle depth were assessed. The target dose coverage between AI-assisted 3D printing template guidance insertion and free-hand insertion techniques was assessed and compared.
Results: The repetition of the planned needle paths was compared with that of the actual needle insertion, a mean deviation of 1.55±0.45 mm was observed. Compared with freehand BT, significant differences were observed in the DVH parameters CTV V100 (p = 0.011), HR-CTV D98 (p = 0.044), bladder D2cc (p = 0.004), and rectum D2cc (p = 0.01) of AI-assisted 3D printing.
Conclusion: This novel technique of AI-assisted 3D printing transvaginal template guidance offers high reproducibility, efficiency, and safety for the insertion BT method in patients with cervical cancer.