EDU 42 - Best Practices in the Multidisciplinary Management of Borderline Resectable and Unresectable Pancreatic Cancer as well as Extrahepatic/Perihilar Cholangiocarcinoma

Moderator(s)

• 

  Higinia Cardenes, MD, PhD

  NewYork-Presbyterian/Weill Cornell Medical Center
  NEW YORK, NEW YORK

Pancreato-biliary cancers, mainly pancreatic cancer and extrahepatic cholangiocarcinoma, are almost uniformly fatal malignancies with increasing incidence and poor prognosis even when diagnosed in the early stages of the disease. They remain a major therapeutic challenge despite the significant medical and surgical advances in the last two decades. Unfortunately, most of the patients present with locally advanced (unresectable) or metastatic disease. Systemic treatment options are limited to a number of systemic chemotherapy regimens, which have shown a modest survival benefit in global tumor population-based clinical studies.

Radiation therapy paradigms continue to evolve with advancements in treatment modalities, delivery techniques, and combination approaches. Despite the advances, there continues to be a controversy on the role of radiation therapy in managing this disease.

The complexity of patients with pancreatic cancer and extrahepatic cholangiocarcinoma requires a personalized and multidisciplinary approach to define how to best combine the different disciplines in each clinical situation.

The aim of this session is to discuss the current state of the art in the management of pancreato-biliary cancers with an emphasis on innovative therapeutic strategies.

Presentations:

• 12:45 PM – 12:47 PM ET

  Introductions
  

  Speaker: Higinia Cardenes, MD, PhD – NewYork-Presbyterian/Weill Cornell Medical Center
• 12:47 PM – 12:51 PM ET

  Case Presentation #1: Borderline Resectable Pancreatic Cancer
  

  Speaker: Higinia Cardenes, MD, PhD – NewYork-Presbyterian/Weill Cornell Medical Center
• 12:51 PM – 1:05 PM ET

  Best Practices in the Surgical Approach of Borderline Resectable and Unresectable Pancreatic Cancer and Extrahepatic Cholangiocarcinoma
  

  Speaker: Nipun Merchant, MD, FACS – University of Miami
• 1:05 PM – 1:19 PM ET

  Borderline and Unresectable Pancreatic Cancer - Role of Ablative Therapies, including Focused Ultrasound and SBRT/SABR
  

  Speaker: Joseph Herman, MD, MS, MSHCM – Northwell Health Cancer Institute
• 1:19 PM – 1:23 PM ET

  Case Presentation #2: Unresectable Perihilar Cholangiocarcinoma
  

  Speaker: Higinia Cardenes, MD, PhD – NewYork-Presbyterian/Weill Cornell Medical Center
• 1:23 PM – 1:37 PM ET

  Hypofractionation and Stereotactic Ablative (Body) Radiotherapy(SBRT/SABR) for Unresectable Perihilar and Distal Cholangiocarcinoma
  

  Speaker: Alejandra Mendez Romero, MD, PhD – Erasmus MC Cancer Institute
• 1:37 PM – 1:51 PM ET

  Role of Systemic Therapy - Targeted Therapy and Immunotherapy in Pancreatic Cancer and Extrahepatic Cholangiocarcinoma
  

  Speaker: Elena Gabriela Chiorean, MD – Fred Hutch Cancer Research, University of Washington
• 1:51 PM – 2:00 PM ET

  Questions and Answers
  

  Speaker: Higinia Cardenes, MD, PhD – NewYork-Presbyterian/Weill Cornell Medical Center