EDU 14 - "Let's Talk About It!" - Biology and Management of Sexual Toxicity Resulting from Prostate Cancer Radiotherapy

Moderator(s)

• 

  Craig Grossman, MD, PhD, MS

  University of South Florida Morsani College of Medicine
  Tampa, FL

Radiation therapy-induced erectile dysfunction (RI-ED) occurs in over 50% of men treated for prostate cancer. The etiologies are likely multifactorial, consisting of a neurological, vascular and endocrine component. Since RI-ED significantly impacts quality of life and therefore may influence a patients decision to pursue radiation treatment, understanding the pathophysiology, preventative measures, and treatment options are important for both the patient and the health care provider. Specific guidelines for RI-ED prevention and rehabilitation in prostate cancer patients have been lacking. However, with the evolution of CT- and MR-guided radiotherapy, novel brachytherapy techniques, and drugs to alter erectile hemodynamics, attempts are being made to mitigate the sexual toxicities of radiotherapy and androgen deprivation therapy.

Presentations:

• 8:00 AM – 8:02 AM ET

  Introductions
  

  Speaker: Craig Grossman, MD, PhD, MS – University of South Florida Morsani College of Medicine
• 8:02 AM – 8:14 AM ET

  Pathogenesis and Pre-Clinical Models of Sexual Toxicities Arising from Prostate Cancer Radiation and Androgen Deprivation Therapy
  

  Speaker: Susan LaRue, DVM, PhD – Colorado State University
• 8:14 AM – 8:26 AM ET

  Radiobiology- and Radiophysics- Based Treatment Strategies to Preserve Sexual Function: Functional Anatomy Sparing Approaches, Altered Fractionation Schedules, and Moderating Androgen Deprivation Ther
  

  Speaker: William McLaughlin, MD – University of Michigan
• 8:26 AM – 8:38 AM ET

  Evaluation and Management of Radiation Therapy- and Androgen Deprivation Therapy-Induced Sexual Dysfunction: Psychosocial, Lifestyle, Medical, and Surgical Options
  

  Speaker: John Mulhall, MD – MSKCC
• 8:38 AM – 8:50 AM ET

  Testosterone Replacement Therapy (TRT) Following Radiation Treatment for Prostate Cancer: Are We Doing a Disservice or Providing a Benefit?
  

  Speaker: Alexander Pastuszak, MD, PhD – University of Utah School of Medicine
• 8:50 AM – 9:00 AM ET

  Questions and Answers
  

  Speaker: Craig Grossman, MD, PhD, MS – University of South Florida Morsani College of Medicine