EDU 08 - Blood-Based Cancer Screening Tests: An Overview of Developing Technologies, Early Prospective Clinical Trial Results and Opportunities for Radiation Oncologists

Moderator(s)

• 

  Nima Nabavizadeh, MD

  Oregon Health & Science University
  Portland, OR

A variety of blood-based cancer screening tests assessing circulating tumor analytes in peripheral blood (including multi-cancer detection (MCD) and single cancer screening tests) are currently being developed with the potential to disrupt current screening paradigms. In this educational session, we highlight the developing technologies, early results from clinical studies testing the efficacy of blood-based genomic tests for cancer screening as well as discuss a proposed professional expansion of the radiation oncology practice relating to the diagnostic workup of individuals who undergo blood-based screening. As blood-based genomic tests for screening have the potential to dramatically alter current paradigms and downstream cancer therapy, it is imperative for radiation oncologists to be aware of important clinical studies, key questions that remain for assessment and regulation, and their potential impact on the field of radiation oncology. All moderators and speakers for this session are ASTRO members/radiation oncologists who have specific interest and experience in the development of blood-based genomic tests for cancer screening.

Presentations:

• 4:45 PM – 4:47 PM ET

  Introductions
  

  Speaker: Nima Nabavizadeh, MD – Oregon Health & Science University
• 4:47 PM – 5:02 PM ET

  Blood-Based Biomarkers for Early Cancer Detection
  

  Speaker: Scott Bratman, MD, PhD – Princess Margaret Hospital
• 5:02 PM – 5:17 PM ET

  Review of Use Case and Early Prospective Trials for Single Cancer Tests to Close Gaps and Reduce Inequities for Recommended Cancer Screening
  

  Speaker: Caitlin Schonewolf, MD, MS – University of Michigan
• 5:17 PM – 5:32 PM ET

  Prospective Results from Early Detection Clinical Trials
  

  Speaker: Sana Raoof, MD, PhD – Memorial Sloan Kettering Cancer Center
• 5:32 PM – 5:47 PM ET

  Case Vignettes from Multi-Cancer Detection Trials and Opportunities for Radiation Oncologists
  

  Speaker: Nima Nabavizadeh, MD – Oregon Health & Science University
• 5:47 PM – 6:00 PM ET

  Questions and Answers
  

  Speaker: Nima Nabavizadeh, MD – Oregon Health & Science University