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Location: Marriott Marquis
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Immunotherapy

Radiation and Cancer Biology
Session Type: Education

EDU 49 - Integrating Focal Therapies and Radiation for Enhances Systemic Immune Modulation

Tuesday, October 1, 2024
2:30 PM – 3:45 PM ET
Location: Room 143

AMA PRA Category 1 Credits 1.25

CAMPEP Credits: 1.25

MDCB Credits: 1.25

This symposium is dedicated to unraveling the emerging field of focal therapies in oncology, with a specific focus on histotripsy, high-intensity focused ultrasound (HIFU) and electroporation. Our journey today goes beyond traditional perspectives, delving into how these innovative treatments target tumors directly and elicit broader systemic and immune responses that are pivotal in cancer therapy. Focal therapies, with precision and targeted approach, have transformed our understanding and management of cancer. Unlike conventional treatments, these modalities offer a unique blend of direct tumor eradication and the induction of systemic immune effects. This dual action presents a new frontier in cancer therapy, opening doors to potential synergies with existing modalities and leading to personalized treatment strategies.
The systemic immune responses elicited by focal therapies represent a paradigm shift in cancer treatment. This symposium will provide a platform to discuss the latest research, clinical applications and future directions in harnessing these responses for improved patient outcomes. A crucial aspect of this symposium will be the potential synergy between these focal therapies and conventional radiation therapy. This session will delve into how integrating these innovative treatments with radiation can enhance overall treatment efficacy. This includes not only a direct impact on the tumor but also a significant enhancement of systemic immune responses, potentially leading to improved patient outcomes. The exploration of this synergy represents a frontier in cancer treatment, promising new avenues for research and clinical practice.

Presentations:

  • 2:30 PM – 2:32 PM ET
    Introductions

    Speaker: Chandan Guha, MD, PhD, MBBS – Montefiore Medical Center, Albert Einstein College of Medicine

  • 2:32 PM – 2:44 PM ET
    Histotripsy - A New Era in Cancer Therapy

    Speaker: Michael Green, MD, PhD – University of Michigan

  • 2:47 PM – 2:59 PM ET
    Combination Therapy with Focused Ultrasound

    Speaker: Elisa Konofagou, PhD

  • 3:02 PM – 3:14 PM ET
    Electroporation: From Localized Treatment to Systemic Response

    Speaker: Bill Moore, MD – NYU Langone Health

  • 3:17 PM – 3:29 PM ET
    Synergizing Focal Therapies with Radiation in Cancer Treatment

    Speaker: Chandan Guha, MD, PhD, MBBS – Montefiore Medical Center, Albert Einstein College of Medicine

  • 3:32 PM – 3:45 PM ET
    Questions and Answers

    Speaker: Chandan Guha, MD, PhD, MBBS – Montefiore Medical Center, Albert Einstein College of Medicine

  • 3:32 PM – 3:45 PM ET
    Questions and Answers

    Speaker: Chandan Guha, MD, PhD, MBBS – Montefiore Medical Center, Albert Einstein College of Medicine