Gastrointestinal Cancer

Patient Reported Outcomes/Survivorship

EDU 57 - Treatment De-Escalation Strategies for Locally Advanced Rectal Cancer

Moderator(s)

• 

  Te Vuong, MD

  McGill University
  Montreal, QC

In the United States, the conventional approach to treating locally advanced rectal cancer has traditionally combined preoperative chemoradiotherapy, total mesorectal excision and adjuvant chemotherapy. The success of this tri-modality treatment has sparked interest in minimizing treatment-related morbidity by de-escalating locoregional therapy. Recent data, including findings from trials such as OPRA and PROSPECT, demonstrate the safety of omitting surgery or radiation, prompting a shift toward a patient-centered approach in rectal cancer treatment. This session will delve into various neoadjuvant treatment strategies aimed at reducing treatment-related morbidity while preserving the outstanding cure rates associated with standard therapy.

Presentations:

• 5:15 PM – 5:17 PM ET

  Introductions
  

  Speaker: Te Vuong, MD – McGill University
• 5:15 PM – 5:17 PM ET

  Introductions
  

  Speaker: Te Vuong, MD – McGill University
• 5:17 PM – 5:32 PM ET

  Omission of Radiation for Rectal Cancer
  

  Speaker: Andrea Cercek, MD – Memorial Sloan Kettering Cancer Center
• 5:32 PM – 5:47 PM ET

  Local Excision for Rectal Cancer
  

  Speaker: Sarah Atkinson, MD – University of Washington
• 5:47 PM – 6:02 PM ET

  Radiation Strategies for Non-Operative Manangement
  

  Speaker: Te Vuong, MD – McGill University
• 6:02 PM – 6:15 PM ET

  Questions and Answers
  

  Speaker: Te Vuong, MD – McGill University
• 6:02 PM – 6:15 PM ET

  Questions and Answers
  

  Speaker: Te Vuong, MD – McGill University